Good morning Wake-Up Watchlisters! While you’re sippin coffee you’ll see stock futures were up on Wednesday ahead of the Federal Reserve’s last announcement of the year. The focus is primarily on the Fed’s policy decision due this afternoon, with investors on alert for signs of an end to interest-rate hikes.

Expect volatility in the markets depending on the Fed’s decision today, however there are still ways to find consistent profits even in volatile markets. Every Wednesday our Head Trading Tactician Bryan Bottarelli uses a trading strategy that’s built to take advantage of a unique market trend. Right now he’s guaranteeing an 80% win rate on these trades.

Click here to unlock Bryan’s latest pick.

Here’s a look at the top-moving stocks this morning.

Vertex Pharmaceuticals (Nasdaq: VRTX)

Vertex Pharmaceuticals is up 7.02% premarket after announcing positive results from its Phase 2 dose-ranging study of its new drug VX-548 to treat numeric pain. The study showed treatment with doses of VX-548 resulted in statistically significant and clinically meaningful reduction in the Numeric Pain Rating Scale at Week 12.

Cava Group (NYSE: CAVA)

Cava Group is up 1.16% premarket after its IPO expiration allowed insiders to sell shares. Roughly 13.6 million shares were traded on Tue4day, which is almost 10 times its normal trading volume. The fact that the stock is up shows buyers still outnumber sellers.